Block & replacement regimen is more cost effective than titration regimen in treating thyrotoxicosis in children, without more harm

نویسندگان

  • MK Anne Kwok
  • PT Cheung
چکیده

Aim The first line treatment of thyrotoxicosis in our unit is anti-thyroid medication for 2 years – longer if unstable control. Since 2010, we changed the anti-thyroid treatment protocol from block and replacement (B&R) to titration regimen (TIT), after the Cochrane review showed that B&R was associated with similar remission rate but more frequent adverse effects than TIT. We aimed at comparing these 2 regimens in our pediatric patients.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A systematic review of drug therapy for Graves' hyperthyroidism.

We assessed the effects of dose, regimen and duration of anti-thyroid drug therapy for Graves' thyrotoxicosis on recurrence of hyperthyroidism, course of ophthalmopathy, adverse effects, health-related quality of life and economic outcomes. We undertook a systematic review and meta-analyses of randomised controlled trials (RCTs). We identified RCTs regardless of language or publication status b...

متن کامل

اثر مصرف چای سبز(Camellia sinensis) بر ریشه‌کنی عفونت هلیکوباکترپیلوری در بیماران مبتلا، در شهر بیرجند

Background and Aim: Helicobacter Pylori is one of the human gastrointestinal tract bacteria that affects more than 50% of the world's population. Eradication of Helicobacter with an effective regimen with low cost and minor side effects is very worthwhile. The aim of this study is to evaluate the rate of Helicobacter Pylori eradication by adding green tea extract to the common 3 drugs regimen c...

متن کامل

Treatment of brucellosis: a systematic review of studies in recent twenty years

Background: The treatment of human brucelosis is controversial. The purpose of this study was to search published clinical trial papers to provide a simple and effective treatment in brucellosis. Methods: Many studies on brucellosis treatment in a twenty- year span from 1993 to 2012 were searched in PubMed, Web of Science (ISI), Scopus, Google Scholar, Magiran, Iranmedex and SID. The studies ...

متن کامل

Juvenile thyrotoxicosis; can we do better?

Thyrotoxicosis remains a frustrating condition for the young person, family, and health professionals involved. The associated symptoms do not always suggest thyroid disease and patients can be unwell for many months before the diagnosis is made. The antithyroid drug regimen used to treat children and adolescents with thyrotoxicosis varies from one unit to another and yet the potentially life t...

متن کامل

Central nervous system relapse prophylaxis in acute lymphoblastic leukemia (ALL) intrathecal chemotherapy with and without cranial irradiation

Background: Central Nervous System (CNS) relapse in acute lymphoblastic leukemia was significantly decreased due to the use of new chemotherapyeutic agents, Intrathecal chemotherapy and cranial irradiation. The purpose of this study was to compare the effectiveness of intrathecal (IT) CNS chemotherapy alone versus combination of IT chemotherapy with cranial irradiation for prevention of CNS rel...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2015  شماره 

صفحات  -

تاریخ انتشار 2015